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KMID : 0617919830010010003
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Wonkwang Oriental Medicine
1983 Volume.1 No. 1 p.3 ~ p.30
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Effect of Moxibustion Treatment on Cephaloridine induced Tubular Damage in Rats
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李德賢
朴鍾國
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Abstract
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To find the clinical effectiveness of moxibustion treatment on cephaloridine induced tubular damage of kidney in albino rats by stimulation of Bi-soo(B 20), Jung-wan(CV 12) and Bi-soo+Jung-wan loci, respectively were studied. And the urine volume, protein contents, alkaline phosphatase(AIP) acivities and electrolyte excretlon in urine, and total protein, albumin, urea nitrogen(SUN), and creatinine(SCr) levels, AIP activities and electrolyte excrtion in serum were determined under several experimental conditions.
The results were obtained as follows:
1. The urine volume volume of 20 hours collected right after the moxibustion stimulation presented increase in the loci of Bi-soo and Jung-wan, while that of 20 hours urine gathered after the moxibustion treatment showed remarkable elevation at the Bi-soo+Jungwan loci.
2. The protein levels and AIP acivities in urine collected right after and 24 hours after the treatment tended to decrease compared with control group, but in case of AIP activities found significantly increase at the Bi-soo+Jung-wan loci, with better resluts when two loci were applied at the same insteaed of individual.
3. The contents of Na^+ in the electrolyte in the 20 hours urine collected 24 hours after the stimulation showed effective increase at the loci of Bi-soo and Bi-soo+Jung-wan, and in case of K^+, it was decreased. The contents of Cl^- of 20 hours urine gathered fight after the moxibustion treatment showed significantly increase only at the loci of Bi-soo.
4. The levels of albumin in serum secured after the collection of 20 hours urine fight after moxibustion treatment showed effective decrease at the Bi-soo locus, but there was no significantly change in other group.
5. The levels of SUN and SCr obtained immediately collection for 20 hours urine was remarkedly decreased at the Bi-soo locus and in the case of the levels of SUN and SCr obtained after 24 hours Bi-soo, and Bi-soo+Jung-wanloci were effectively eliminated.
6. Alp activities in serum obtained right after the collection of the 20 hours urine was elevated at the Bi-soo locus, while in the case of AIP activities in serum obtained after 24 hours after moxibustion treatment, there was significant increase only at the locl of Bi-soo+Jung-wan.
7. But the moxibustion stimulation of Bi-soo, Jung-wan, and Bi-soo+Jung-wan loci seemed to have no effect on the contents of Na^+, K^+ and Cl^- of electrolyte in serum.
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